Choice "B" is correct. Where a person is tricked into signing something that she does not know is a negotiable instrument, there has been a fraud committed in the execution of the document, and this defense is available even against a holder in due course.
Choice "d" is incorrect. The defense of mistake is not available against a holder in due course.
Choice "c" is incorrect. Duress occurs when an innocent party is threatened into committing an act that the innocent party would not normally agree to perform. Whether the defense can be raised against a holder in due course depends on the seriousness of the threat, but here there is no threat.
Choice "a" is incorrect. Fraud in the inducement occurs when one is promised value in exchange for an instrument and the promisor does not intend to and does not give that value. Such a defense is not valid against a holder in due course and is not supported by the facts here anyway.